With mechanical thrombectomy now representing standard of care for treatment of acute ischemic stroke secondary to large vessel occlusion, identifying adjunctive techniques that result in improved outcomes for patients with LVO has become an issue of increasing importance. A number of retrospective studies have demonstrated that flow arrest during the clot retrieval process results in less clot fragmentation, lower rates of distal emboli, higher revascularization rates and improved rates of good neurological outcome.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
155
Use a balloon guide catheter in the mechanical thrombectomy
Use a non-balloon guide catheter in the mechanical thrombectomy
Suzhou Municipal Hoapital
Suzhou, Anhui, China
NOT_YET_RECRUITINGXuan Wu Hospital,Capital Medical University
Beijing, Beijing Municipality, China
RECRUITINGLu He hospital, Capital Medical University
Beijing, Beijing Municipality, China
RECRUITINGShengli Oilfield Central Hospital
Dongying, Shandong, China
NOT_YET_RECRUITINGNanyang City Center Hospital
Nanyang, China
RECRUITINGThe First Affiliated Hospital of Zhengzhou University
Zhengzhou, China
NOT_YET_RECRUITINGDistal embolization,
Time frame: After mechanical thrombectomy, usually within 3 hours
Modified thrombolysis in cerebral infarction 2b/3,
Time frame: After mechanical thrombectomy, usually within 3 hours
Modified thrombolysis in cerebral infarction
Time frame: After mechanical thrombectomy, usually within 3 hours
Modified thrombolysis in cerebral infarction 2b/3 after the first pass
Time frame: After the first pass, , usually within 3 hours
First pass recanalization rate
Time frame: After the first pass, , usually within 3 hours
Number of passes
Time frame: After mechanical thrombectomy, usually within 3 hours
Procedure time
Time frame: From the procedure start to the end, usually within 3 hours
National Institutes of Health Stroke Scale
Scores on the National Institutes of Health Stroke Scale (NIHSS) range from 0 to 42, with higher scores indicating more severe neurologic deficits.
Time frame: 7 days or discharge
Symptomatic intracranial hemorrhage
Time frame: 24 hours
Modified Rankin Scale
Scores on the modified Rankin scale of functional disability range from 0 (no symptoms) to 6 (death).
Time frame: 90 days
Mortality
Time frame: 90 days
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