Obstructive sleep apnea (OSA) is a common clinical condition, involving the development of arterial hypertension. A Meta analysis study have shown that isometric hand grip training promotes blood pressure reduction. It is going to be conducted a clinical trail to determine the effects of hand grip training in OSA patients to change the arterial hypertension.
Background: obstructive sleep apnea (OSA) is a common clinical condition, involving the development of arterial hypertension. Meta analysis study have shown that isometric hand grip strength promotes blood pressure reduction, and its reduction is higher than that observed after aerobic training. Objective: to analyze the effects of the isometric hand grip on blood pressure changes of patients with uncontrolled arterial hypertension with OSA. Methods: a randomized controlled trial involving 18 adults with OSA and uncontrolled arterial hypertension of both sexes, randomized between control group (receive general guidelines) and hand grip group. 12 weeks of training with load equivalent to 30% of maximum voluntary capacity was performed. All participants will be submitted for evaluation of blood pressure (BP) central and brachial, pulse wave velocity, full polysomnography,before and after the study protocol (the change from the baseline at 12 weeks). Expected results: the authors believe that hand grip training can change (reduce) blood pressure in patient with OSA.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
18
The patients at the Hand Grip group will perform 12 weeks of hand grip exercises, three times/week for 16 minutes with time to rest.
The patients will receive verbal orientations about the OSA and the arterial hypertension.
Pronto Socorro Cardiológico de Pernambuco - Procape
Recife, Pernambuco, Brazil
RECRUITINGChange at ambulatory blood pressure monitoring
24h of monitoring blood pressure
Time frame: Change from the baseline ambulatory blood pressure monitoring at 12 weeks
Change at blood pressure
Three measurement of brachial blood pressure
Time frame: Change from the baseline brachial blood pressure at 12 weeks
Chance at Apnea-Hypopnea Index (AHI)
Index obtained by the Polysomnography to detect the level of Apnea-Hypopnea Index. The higher level, the worse the disease. The value of the AHI between 5 to 15 events/hour means mild disease. AHI between 16 to 30 events/hour means moderate disease, and more than 30 events/hour means severe disease.
Time frame: Change from the baseline AHI at 12 weeks
Change at Pulse wave velocity
To evaluate the pulse wave velocity (femoral, carotid and aortic) to detect the occurrence of arterial disease.
Time frame: Change from the baseline pulse wave velocity at 12 weeks
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