Prospective multicenter observational study to assess molecular drivers of metastatic breast cancer and disease evolution upon therapeutic pressure. The main aim is to develop and validate prognostic, predictive and pathogenic markers in clinically well-characterized population-based material of breast cancer tumors and the corresponding normal tissue.These data will be used to characterize recurrent breast cancer on a molecular level, study tumor evolution, develop biomarkers of response/resistance to targeted therapy in the metastatic setting, enroll patients on targeted treatment clinical studies and to elucidate mechanisms of resistance to therapy.
Study Type
OBSERVATIONAL
Enrollment
2,000
We will perform targeted exon sequencing on paraffin embedded tissues from metastatic breast cancer
Lund University Hospital
Lund, Sweden
RECRUITINGLund University Hospital
Lund, Sweden
RECRUITINGSurvival
Prospective recording of treatment interventions and molecular characteristics in metastatic breast cancer patients until the date of Death.
Time frame: 10 years
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