Lactoferrin Versus Ferrous Sulfate in Iron-deficiency During Pregnancy

Inclusion Criteria: * Pregnant women with single fetus. * Second trimester (14-20weeks of gestation). * Normal Hemoglobin level: more than10g\\dl. * Serum ferritin less than 15 mcg / L Exclusion Criteria: * Other type than iron-deficiency anemia (thalassemia, hemolytic anemia … etc.) * Any other chronic diseases (bronchial asthma, renal or hepatic, hematological or cardiovascular diseases … etc.) * Having hypersensitivity to iron preparations. * Treatment with any other iron preparation in the last month. * History of peptic ulcer, oesophagitis or hiatal hernia. * Medical disorders with pregnancy. * Need for alternative parenteral route to blood transfusion when rapid increase is required (perioperative anemia-severe anemia in late pregnancy-postpartum anemia) . * Bleeding in early pregnancy. * Refusal to participate in the study. * Family history of thalassemia-sickle cell anemia or malabsorption syndrome. * Recent blood transfusion. * Inflammatory bowel disease as intolerance of oral therapy but tolerated to parenteral route.