A Study to Evaluate the Appropriateness of the Voriconazole Dosing Regimen

Inclusion Criteria: * Those who have been informed of the nature of the trial and have voluntarily agreed to participate in this study and have signed an IRB approved consent before all screening tests * Healthy Korean male and female volunteers aged 20 to 45 * Those with a body weight of 50 kg or more and less than 90 kg and a body mass index (BMI) of 18 or more and less than 27 (BMI(kg/m2) = body weight (kg)/{height(m)}2 * CYP2C19 EM or PM Exclusion Criteria: * Subjects with clinical evidence of significant respiratory, circulatory, renal, hepatic, endocrine, blood, neuropsychiatric, skeletal or other chronic diseases, alcohol or drug addiction * Subjects with a history of gastrointestinal disorders (Crohn's disease, ulcers, acute or chronic pancreatitis, etc.) or gastrointestinal surgery (excluding simple cecal surgery or hernia surgery) that may affect the absorption of the test drug * Those with a history of substance abuse within the last 2 months * Those who have taken any prescribed medicines or herbal medicines within 2 weeks prior to the date of the first medicines, or those taking any general medicines (OTC) or vitamin preparations (eligible if the other conditions are reasonable according to the judgment of the investigator) * Those who donate blood within 30 days before the date of the first dose or who have participated in the clinical study of other clinical trial drugs or marketed drugs within 3 months * Those who have had significant adverse reactions such as hypersensitivity reactions to azole drugs including drugs for clinical research * Those who are not planning on or planning to have a pregnancy during the trial and are not able to use a recognized method of contraception (eg, sterilization surgery of the person and partner, intrauterine contraceptive device, or diaphragm contraception (such as diaphragm or condom use) * Persons who are continuously drinking (21 units / week, 1 unit = 10 g of pure alcohol) or who can not abstain from 3 days before the first dose to the end of the clinical trial * Those who smoked more than 10 cigarettes per day for the last 3 months or who can not quit smoking 3 days before the first dose * Those who consume grapefruit / caffeine-containing food within 3 days of the first dose or who cannot be prohibited during the clinical study period * Screening tests for urine pregnancy (β-hCG) positive or lactating women * Those with genetic problems such as galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption. * A person who is found to be unsuitable for participation in clinical research due to safety laboratory results or other reasons