A Study Designed to Evaluate the Safety and Pharmacokinetics of Intravenously Administered Superoxide Dismutase Mimetic GC4711 in Healthy Volunteers

Inclusion Criteria: 1. Healthy men and women between 18 and 50 years 2. Subjects who provide written informed consent 3. Body Mass Index (BMI) of 18 to 32 kg/m2 and weighing at least 50 kg 4. Subjects in general good health 5. Blood pressure and pulse within normal limits 6. Male subjects must practice effective contraception 7. Female subjects must: * Have a negative serum pregnancy test during * Be non-lactating; * Be at least 2 years postmenopausal, surgically sterile, or practicing effective contraception. Exclusion Criteria: 1. History of clinically significant illness or medical history which would preclude them from the study. 2. Known contraindication, hypersensitivity and/or allergy to study drugs 3. Use of any prescription or over-the-counter medication within one week prior to study drug administration 4. Anticipated need for any medication during the study 5. Use of nitrates or erectile dysfunction drugs such as phosphodiesterase type 5 (PDE 5) inhibitors 6. Use of other drugs that may, in the judgment of the Investigator, create a risk for a precipitous decrease in blood pressure 7. Presence of orthostatic hypotension at screening 8. Use of any vitamin or mineral supplement 24 hours before dosing or throughout study 9. Positive human immunodeficiency virus (HIV), hepatitis B (HBV) or hepatitis C (HCV) 10. Known history of substance abuse, drug addiction, or alcoholism within 3 years 11. Anticipated inability to abstain from alcohol, tobacco, or caffeine use from 48 hours before the administration of study drug and throughout the the study; 12. Positive drug and alcohol toxicology screens during Screening 13. History of smoking or any use of a tobacco product within 6 months 14. Donation of blood or blood products within 30 days before Baseline and throughout the study; 15. Mentally unstable or incapable of being compliant with the protocol 16. Receipt of an investigational test substance within 3 months before the administration of study drugs, or anticipated receiving any study drugs 17. Subject has previously participated in this study, or in a prior Galera study