The Effect of the ALDH2 Gene Polymorphism on the Propofol Potency for Inducing Loss of Consciousness

Shanghai Zhongshan Hospital100 enrolled

Overview

The aim of this study is to determine whether ALDH2 gene polymorphisms (G/G, G/A A/A) have effect on the potency of propofol.

Study Type

OBSERVATIONAL

Enrollment

100

Patients will be induced to unconsciousness using propofol intravenously.

Sex: MALEMin age: 50 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * ASA II Exclusion Criteria: * ASA III-IV * OSAS * hepatic and renal insufficiency

Effect-site concentration

patient's effect-site concentration when he/she loss consciousness

Time frame: immediately after patient lose his/her consciousness

Kefang Guo, MD

CONTACT

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