Low Residue Diet During 3 Days vs 1 Day Prior Colonoscopy

Parc Taulí Hospital Universitari858 enrolled

Overview

Colonoscopy is the gold-standard for the evaluation of the colorectal mucosa. Colonoscopy quality indicators are the adenoma detection rate, the rate of cecal intubation and the bowel preparation. The role of diet in preparing for colonoscopy is not fully established. Currently there is not enough evidence available to choice between 3 days of low residue diet versus 1 day. The research hypothesis is that the low residue diet offers a non-inferior bowel preparation and an improved tolerance.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

TRIPLE

Enrollment

858

Conditions

Colonoscopy Colon Adenoma Colorectal Neoplasms Inflammatory Bowel Diseases Colon Disease

Interventions

1 day low residue dietOTHER

Patients are interviewed and instructed by a nurse prior the colonoscopy. They receive oral and written dietary information. In case of morbidity associated with bad preparation they are given bisacodyl the night before the colonoscopy.

3 day low residue dietOTHER

Outcomes

Primary Outcomes

Bowel preparation

Measured with the Boston Bowel Preparation Scale from 0 until 9. 9 represents an excellent preparation.

Time frame: During the colonoscopy

Secondary Outcomes

Diet tolerance

Using Likert scale. From 1 to 5, lower is better tolerance.

Time frame: It is reported before entering the endoscopy room. Regarding the 3 or 1 days on low fiber diet depending on which study group is the participant.

Preparation tolerance

Using Likert scale. From 1 to 5, lower is better tolerance.

Time frame: It is reported before entering the endoscopy room. Regarding the 3 or 1 day on bowel preparation depending on which study group is the participant.

Adenoma detection rate

Proportion of colonoscopies with detection of colorectal cancer or adenoma excluding distal hyperplastic

Time frame: up to 2 weeks after colonoscopy depending on pathology department workload.

Endoscopic diagnosis

Final endoscopic diagnosis. For example; normal, diverticulosis, polyps, colorectal cancer, etc.

Time frame: It is assessed during the colonoscopy and will be reported the same day.

Cecum intubation rate

Cecum intubation will be assessed during each colonoscopy if the endoscope reaches the cecum.

Time frame: It will be calculated through study completion, approximately 1 year, for all the study period using all participants having the colonoscopy done

Intubation time

time lapse from the start of the exploration until cecum is reached.

Time frame: it is assessed from the start of the colonoscopy until cecum is reached (1 day)

Withdrawal time

Time lapse between cecum withdrawal the end of the exploration.

Time frame: it is assessed from at the beginning of the withdrawal of the colonoscope until the colonoscopy is finished. (procedure)