Dental Caries Prevention by a Natural Product

Cairo University81 enrolled

Overview

The objective is to conduct an RCT to evaluate the effectiveness of Licorice in comparison to standard caries preventive measures for the prevention of new carious lesions in high caries risk patients.

Research hypothesis (Null hypothesis): The present clinical trial will be conducted to reject or accept the null hypothesis that using Licorice extract mouth wash in addition to standard preventive measures will not differ from using standard preventive measures alone in preventing incidence of new carious lesions. PICOTS: P: Population with high caries risk patients I: Use of licorice. I2: Use of chlorhexidine C: Use of standard preventive measures (tooth brushing, tooth paste, interdental cleaning). O.1: Primary outcome is incidence of new carious lesions T: Time for measurement is 12 months S: A Randomized controlled clinical trial (Parallel study)

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Enrollment

Conditions

Dental Caries

Interventions

LicoriceOTHER

Natural herbal product

Eligibility

Sex: ALLMin age: 18 YearsMax age: 25 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with high caries risk, * 18-25 years, * Males or females, * Medically free patients, * Patients approving to participate in the study. Exclusion Criteria: * Patients who were on antibiotic therapy or corticosteroid therapy for 30 days before the examination, * Patients had history of professional cleaning in the last 15 days, * Patients with exposed pulp, * Evidence of parafunctional habits, * Patients with developmental dental anomalies, * Patients undergoing or will start orthodontic treatment, * Patients with removable prosthesis, * Periapical Abscess or Fistula.

Locations (1)

Conservative and Esthetic Dentistry Department-Faculty of Dentistry- Cairo University

Cairo, Choose Any State/Province, Egypt

Outcomes

Primary Outcomes

Incidence of new carious lesions

Appearance of new carious lesions within the study duration

Time frame: 12 months

Data from ClinicalTrials.gov

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