Evaluation of Micro-osteoperforation on Rate of Maxillary En-masse Retraction

Inclusion Criteria: * Females with an age ranging between 16-30 years. * Malocclusion that requires bilateral extraction of the maxillary first premolars and anterior segment retraction; Angle class I mal-occlusion with bi-alveolar dental protrusions or class II division 1. * Healthy dental and periodontal condition with a good oral hygiene * Absence of degenerative conditions. * Full set of permanent dentition. Exclusion Criteria: * Medically compromised patients. * Previous orthodontic treatment * Patients suffering from any congenital, hereditary or systemic diseases or asymmetries that might have an influence on tooth movement * Chronic use of any medications affecting orthodontic tooth movement (eg: NSAIDs). * Active periodontal affection or severe gingival inflammation.