This is a Single arm clinical study evaluating the safety and efficacy of hAECs in preventing aGVHD after HSCT.
A dose escalation study evaluating the safety and efficacy of human amniotic epithelial cells( hAECs) in preventing acute graft-versus-host(aGVHD) disease after hematopoietic stem cell transplantation(HSCT). The doses were 1×10\^6、2×10\^6、5×\^6 cell/kg, successively.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
PREVENTION
Masking
NONE
Enrollment
27
Human amniotic epithelial cells(hAECs)
Peking University Institute of Hematology
Beijing, Beijing Municipality, China
RECRUITINGPeking University People's Hospital
Beijing, Beijing Municipality, China
RECRUITINGOccurrence of adverse events
Safety of HSCT combined with hAECs infusion;
Time frame: 1 year
GVHD
Occurrence of Graft-versus-host disease after hAECs infusion
Time frame: 1 year
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