NCT03764930 - Attention to Retinoblastoma Diagnosed in the Trauma Setting | Crick

Overview

To study the clinical characteristics and treatment outcomes of patients who experienced inadvertent trauma before diagnosis of retinoblastoma.

Retrospective study of the clinical characteristics and treatment outcomes of patients who experienced inadvertent trauma before diagnosis of retinoblastoma and to alert ophthalmologists to the possibility of RB in children presenting with or without trauma-related symptoms and signs.

Study Type

OBSERVATIONAL

Enrollment

10

Conditions

Retinoblastoma Wounds and Injury

Interventions

Unsuspected RetinoblastomaOTHER

To study the clinical characteristics and treatment outcomes of patients who experienced inadvertent trauma before diagnosis of retinoblastoma.

Eligibility

Sex: ALLMin age: 1 MonthMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * The consecutive patients with RB managed at the ocular oncology service of Zhongshan Ophthalmic Center, Sun Yat-sen University, between January 2013 and August 2018. Exclusion Criteria: * The patients who didn't have undergone trauma before diagnosis of RB.

Locations (1)

Zhongshan Ophthalmic Center, Sun Yat-sen University

Guangzhou, Guangdong, China

Outcomes

Primary Outcomes

Survival Status

Outcome at last follow-up

Time frame: between January 2013 and August 2018

Secondary Outcomes

Trauma incidence of RB patients

We reviewed the computerized diagnostic records of consecutive patients with RB managed at the ocular oncology service of Zhongshan Ophthalmic Center, Sun Yat-sen University, between January 2013 and August 2018. The charts of those patients who had undergone trauma before diagnosis of RB were selected. In addition, we identified the preschool-aged children (age 0-6 years) who underwent surgical treatment for ocular trauma at our hospital during the corresponding period. Then, we calculated the incidence of trauma among RB patients.

Time frame: between January 2013 and August 2018

RB incidence of pre-school patients with trauma history

We reviewed the computerized diagnostic records of consecutive patients with RB managed at the ocular oncology service of Zhongshan Ophthalmic Center, Sun Yat-sen University, between January 2013 and August 2018. The charts of those patients who had undergone trauma before diagnosis of RB were selected. In addition, we identified the preschool-aged children (age 0-6 years) who underwent surgical treatment for ocular trauma at our hospital during the corresponding period. Then, we calculated the incidence of RB among pre-school patients with trauma history.

Time frame: between January 2013 and August 2018