Pharmacokinetic Non-interaction Study With a Fixed-dose Combination Tablet With Tramadol and Diclofenac

Inclusion Criteria: * Man or woman between 18 and 55 years of age. * Women with use of a barrier method as a contraceptive. * Body mass index equal to or above 18.0 and equal to or less than 27.0 kilograms per square meter. * Clinically healthy. If the clinical history, the registration of vital signs and the physical examination did not show abnormal deviations that avoid their participation in a clinical study. * Without a history of allergic reactions to the study drug. * Stable vital signs during the selection (heart rate, respiratory rate, blood pressure at rest and axillary body temperature). * Laboratory studies: complete blood count, blood chemistry of 24 items, urinalysis, anti-human immunodeficiency virus (HIV) 1, anti-HIV2, anti-hepatitis B surface antigen (HBs) and anti-hepatitis C virus (HCVs) antibodies, and serologic test for syphilis \[Venereal Disease Research Laboratory test\]) within normal ranges according to the reference laboratory, or that the deviations are not clinically significant. If the deviation has no clinical significance, it may be justified the inclusion of the participant to the clinical study. The age of the report of the clinical laboratory studies must not be greater than 3 months. * Electrocardiogram (ECG) with no pathological alterations, with validity of no more than 3 months. * The participant accepts the restrictions and indications described in the protocol and internal regulations. * The participant has read and understood the relevant aspects of the clinical study and gives its authorization for participation by signing the informed consent form before inclusion on the clinical study and performing any procedure. Exclusion Criteria: * Findings in the clinical history, vital signs and/or physical examination that show abnormal conditions of the general state of health of the participant that avoid its participation in a clinical study. * Recent exposure to the study drug between the 30 days prior or any other medication by prescription or self consumed between the 14 days prior to the start of the study, or that do not accept to avoid its consumption during the course of the study. * Surgery during the 30 days prior to the start of the study. * Suspicion or evidence of infection by Human Immunodeficiency Virus (HIV), hepatitis B virus (HBV) and/or hepatitis C virus (HCV). * Serologic test for syphilis (Venereal Disease Research Laboratory test) positive. * Known hypersensitivity to any medication. * Blood donation equal to or above 1 unit (0.5 liters) during the 30 days prior to the selection. * Participants who have special food requirements or food restrictions. * Women in the breastfeeding period and/or pregnant. * Positive results in the qualitative test of pregnancy in urine (only women). * Positive result in the qualitative detection of drugs of abuse. * Participation in a clinical study Phase 1, 2 or 3 or bioavailability/ bioequivalence studies during the 3 months previous to the selection. * The participant does not give his or her authorization to participate in the study through the signing of an informed consent, or is not willing to follow the indications and/or restrictions of the protocol and rules of the procedure. * The participant is vulnerable or potentially vulnerable by which cannot freely express his/her consent by subordination of the principal investigator or by coercion of any third party.