Purpose: In this study, the investigators compared the effectiveness of peripheral nerve block (greater occipital nerve block with supratrochlear nerve block) versus topiramate as detoxification therapies in chronic migraine patients with medication overuse headache. Methods: At least ninety chronic migraine patients with medication overuse headache are aimed to include in this study. Patients will be divided into the two groups. The first group will receive topiramate (n=45, estimated) and the second group will receive nerve block (n=45, estimated) as detoxification therapy. Patients' records regarding the visual analog scale (VAS) scores and headache frequencies are aimed to be collected before and after the therapy. Comparisons regarding VAS scores, headache frequencies, 50% responder rates and 75% responder rates will be performed in between topiramate and nerve block groups.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
90
An antiepileptic agent used for migraine prophylaxis.
An injection to paralyze the occipital and supratrochlear nerves.
Mustafa Ceylan
Erzurum, Turkey (Türkiye)
Visual Analog Scale
Range Pain 0-10, 0: No pain, 10: Worst Pain
Time frame: Post treatment (4 weeks later)
Attack Frequencies
Number of headaches patients suffer in a month.
Time frame: Post treatment (4 weeks later)
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