Our aim to study the efficacy of bupivacaine 0.25% with dexamethasone and that of bupivacaine 0.25% alone in transversus abdominis plane (TAP) block for postoperative analgesia in patients undergoing an elective Caesarean section. * Group 1: bupivacaine 0.25% + dexamethasone 8 mg * Group 2: bupivacaine 0.25% A prospective Randomized Interventional double-blind study.
The pain and discomfort following cesarean delivery are mostly due to the abdominal wall incision and dissection of muscles; it delays early ambulation and breastfeeding. This can lead to postoperative complications such as thromboembolic disorders. So, providing an effective and safe postoperative analgesic method seems to be mandatory. Opioid analgesia remains the most effective means of relieving pain in a wide variety of conditions; however, it may cause adverse effects such as nausea, vomiting, pruritus, urinary retention, and respiratory depression. As the analgesia and the side effects of opioids are dose-dependent, a multimodal approach may enhance analgesia, which in turn would decrease the side effects . Mc Donnell and colleagues have reported that a transversus abdominis plane (TAP) block can decrease the postoperative pain following abdominal surgery. The landmarks of this block were first described in 2001 by Rafi. The TAP block has been performed for postoperative analgesic control in patients undergoing radical prostatectomy, hysterectomy, cesarean delivery under spinal anesthesia, and laparoscopic surgery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
120
TAP block with 20 ml of 0.25% bupivacaine bilaterally
TAP block with 4 mg dexamethasone bilaterally
TAP block with 4 mg placebo to dexamethasone bilaterally
Aswan University
Aswān, Egypt
Visual analog score for pain during movement
movement-evoked pain measurements ranging from 0 to 10, where 0 no pain and 10 maximum pain
Time frame: 6 hours post operative
Visual analog score during rest
ranging from 0 to 10, where 0 no pain and 10 maximum pain
Time frame: 48 hours postoperative
number of patients need Fentanyl consumption
number of patients need Fentanyl consumption
Time frame: 48 hours postoperative
number of days patients stay in hospital
calculation of number of days patients stay in hospital
Time frame: 4 weeks
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.