The aim to study the efficacy of bupivacaine 0.25% with dexamethasone and that of bupivacaine 0.25% alone for erector spinae plane block for postoperative analgesia in patients undergoing total abdominal hysterectomy Group 1: bupivacaine 0.25% + dexamethasone 8 mg * Group 2: bupivacaine 0.25% * Group3: control group A prospective Randomized Interventional double-blind study.
Optimal dynamic analgesia is recognized as the key to enhanced recovery following open abdominal surgery. In the last decade, there has been a significant shift away from thoracic epidural analgesia (TEA) that has been long considered as the gold standard. Various techniques have tried to replicate the analgesic efficacy of TEA. They include transversus abdominis plane analgesia (TAP), rectus sheath analgesia (RS), wound infusion analgesia (WI) and trans muscular quadratus lumborum analgesia. However, each of these techniques has specific limitations that prevent them from being the analgesic technique of choice for all open abdominal surgeries. Chin et al first described the erector spinae plane (ESP) block for providing analgesia following ventral hernia repair. The unique feature of the ultrasound-guided truncal blocks is that in all of these techniques, in contrast to peripheral nerve blocks, no nerve or plexus needs to be identified: Local anesthesia (LA) is injected in a particular muscle plane, in which the injectate spreads and reaches the intended nerves. This simple mechanism has made delivery of nerve blocks easy and versatile.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
150
Bilateral TAP block with 20 ml of 0.25% bupivacaine
Bilateral TAP block with 4 mg/kg dexamethasone diluted with isotonic saline.
Bilateral TAP block with placebo to dexamethasone.
Aswan University
Aswān, Egypt
Visual analog score for pain during movement
movement-evoked pain measurements ranging from 0 to 10, where 0 no pain and 10 maximum pain
Time frame: 24 hours post operative
Visual analog score for pain during rest
ranging from 0 to 10, where 0 no pain and 10 maximum pain
Time frame: 24 hours postoperative
number of patients need Fentanyl consumption
calculation of the number of patients need Fentanyl consumption
Time frame: 24 hours postoperative
number of days patients stay in hospital
calculation of number of days patients stay in hospital
Time frame: 4 weeks
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Bilateral TAP block with placebo to bupivacaine.