Online Mindfulness-based Tic Reduction (Phase Two)

Bowdoin College37 enrolled

Overview

Tourette Syndrome (TS) and Persistent Tic Disorder (PTD) are chronic and potentially disabling neurobiological conditions. Although a range of pharmacological and psychosocial treatments exists, a significant number of individuals either do not respond to the current treatments or find them unacceptable. Thus, it is essential that researchers continue to develop and test novel treatment approaches. In this randomized controlled trial the investigators will compare two different online group-based interventions for tics: a mindfulness-based program (Mindfulness-based Intervention for Tics (MBIT), and a psychoeducational and supportive therapy program (Tic Information and Coping Strategies (TICS)). The purpose of this study is to determine which intervention is more helpful for adults with a tic disorder.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Tourette Syndrome Persistent Tic Disorder

Interventions

Tic Information and Coping StrategiesBEHAVIORAL

Psychological Intervention that focuses on learning more about tics, practicing a range of strategies for coping with tics (e.g., relaxation, effective communication), and discussing challenges commonly experienced by individuals with tics.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. be 18 years of age or older, 2. possess a primary diagnosis of Tourette Syndrome or Persistent Tic Disorder, 3. be fluent in English 4. reside in the United States, 5. either not be taking any tic suppressant medication or other psychotropic medication or be at a stable dose for 8 weeks prior to the baseline assessment and throughout the study Exclusion Criteria: 1. be receiving concurrent psychotherapy for the duration of the study 2. have prior extensive experience with mindfulness and/or meditation and 3. have another medical or psychological condition that would prevent the individual from fully engaging in the study or require a higher level of care (e.g., suicidality).

Locations (2)

Bowdoin College

Brunswick, Maine, United States

Massachusetts General Hospital

Boston, Massachusetts, United States

Outcomes

Primary Outcomes

Change in Yale Global Tic Severity Scale (YGTSS) Total Tic Severity Score

Clinician-rated measure of tic severity

Time frame: Screening, Week 0, Week 9, Week 13, Week 35

Secondary Outcomes

Clinical Global Impressions Scale

Time frame: Weeks 0, 9, 13, 35

Adult Tic Questionnaire

Time frame: Weeks 0, 9, 13, 35

Yale-Brown Obsessive Compulsive Scale

Time frame: Weeks 0, 9, 13, 35

Attention-Deficit Hyperactivity Rating Scale

Time frame: Weeks 0, 9, 13, 35

Depression Anxiety Stress Scale

Time frame: Weeks 0, 9, 13, 35

Premonitory Urge to Tic Scale

Time frame: Weeks 0, 9, 13, 35

Tic Rating Form

Time frame: Weeks 1-8

Problem Rating Form

Time frame: Weeks 1-8

Patient Health Questionnaire-9

Time frame: Weeks 0, 9, 13, 35

Work and Social Adjustment Survey

Time frame: Weeks 0, 9, 13, 35

Five Facet Mindfulness Questionnaire

Time frame: Weeks 0, 4, 8, 9, 13, 35

Credibility and Expectancy Questionnaire

Time frame: Week 3

Patient Satisfaction Questionnaire

Time frame: Week 9

Self Compassion Scale

Time frame: Weeks 0, 9, 13, 35

Affective Reactivity Index

Time frame: Weeks 0, 9, 13, 35

Brief Irritability Test

Time frame: Weeks 0, 9, 13, 35