Preoxygenation Using THRIVE Versus Facemask in Parturients

University of British Columbia91 enrolled

Overview

This study aims to determine the duration for pre-oxygenation using THRIVE and facemask for parturients.

We aim to determine the duration required for THRIVE and facemask preoxygenation in parturients for them to achieve ETO2 \>90%.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Preoxygenation

Interventions

Facemask preoxygenationDEVICE

Standard facemask preoxygenation

THRIVE preoxygenationDEVICE

Preoxygenation using transnasal humidified rapid insufflation ventilatory exchange (THRIVE).

Eligibility

Sex: FEMALEMin age: 19 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Pregnant patients ≥36 weeks gestation. * Non-laboring patients admitted for elective Cesarean delivery under neuraxial anesthesia or induction of labor. * American Society of Anesthesiologists (ASA) class 2. Exclusion Criteria: * Any medical conditions that are likely to affect gas exchange. * Obstructed nasal passage. * Unable to tolerate a tight fitting facemask. * Body Mass Index ≥40 kg/m2. * Patients who are in active labor (i.e. cervical dilation ≥4cm). * Patients who are unable to give informed consent.

Locations (1)

BC Women's Hospital

Vancouver, British Columbia, Canada

Outcomes

Primary Outcomes

Preoxygenation Duration

Duration to achieve EtO2 \>=90% after tidal volume breathing using THRIVE and facemask pre-oxygenation.

Time frame: Maximum 8 minutes

Secondary Outcomes

Proportion to Reach End Tidal Oxygen (ETO2) of 90 Percent at 3 Minutes

Time frame: 3 minutes of pre-oxygenation

Proportion to Reach EtO2 of 90 Percent at 4 Minutes

Time frame: 4 minutes of preoxygenation

Proportion to Reach EtO2 of 90 Percent at 5 Minutes

Time frame: 5 minutes of preoxygenation

Proportion to Reach EtO2 of 90 Percent at 6 Minutes

Time frame: 6 minutes of preoxygenation

Proportion to Reach EtO2 of 90 Percent at 7 Minutes

Time frame: 7 minutes of preoxygenation

Proportion to Reach EtO2 of 90 Percent at 8 Minutes

Time frame: 8 minutes of preoxygenation

Comfort Score

Patients were asked to rate their comfort with the device on a 5 point Likert Scale: (1=completely uncomfortable, 2=slightly uncomfortable, 3=neutral, 4=slightly comfortable, 5= completely comfortable)

Time frame: 1 minute after data collection

Acceptability Score

Acceptability was measured with a 5-point Likert Score (1= unacceptable, 2=slightly unacceptable,3=neutral, 4=slightly acceptable, 5=acceptable).

Time frame: 1 minute after data collection

Data from ClinicalTrials.gov

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