A Comparative Study of Brain Structure and Amyloid Load in MCI Patients

Chinese University of Hong Kong

Overview

Older people with DM are at greater risk of cognitive decline than their counterparts with DM. Cognitive impairment in older people with DM may be associated with non-AD related brain atrophy and white matter disease. The investigators therefore propose to compare DM and non-DM older people with amnesic MCI in brian volumes, white matter disease and amyloid load. 30 older people with aMCI, 30 older people with aMCI and DM, age 65-85 will be recruited. They all will have amyloid PET scan and MRI brain scan.

Study Type

OBSERVATIONAL

Conditions

Mild Cognitive Impairment

Eligibility

Sex: ALLMin age: 65 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * MCI patients Exclusion Criteria: * Patients with depression

Locations (1)

The Chinese University of Hong Kong

Hong Kong, Hong Kong

Outcomes

Primary Outcomes

Amyloid load

Time frame: Two years

Data from ClinicalTrials.gov

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