The study is a prospective-observational, explorative single-centre cohort study aimed to examine the influence of the peripheral atherosclerotic plaque volume on short and long term morbidity and mortality in patient after coronary artery bypass grafting (CABG). Atherosclerotic disease (IMT, plaque volume) will be measured with a ultrasound system (IMT measurements and 3D quantitative plaque volumetric). Hemodynamic and flow profiles of the internal thoracic arteries will be evaluated additionally with US. These parameters will be measured pre-CABG. Morbidity will be evaluated using quality of life questionnaires (EQ-5D-3L, IPAQ). Major adverse cardiovascular events (MACE) will be the primary endpoint. The atherosclerotic burden will be compared with established risk scores (EuroSCORE, STS-Score, SYNTAX Score, FORECAST.
Study Type
OBSERVATIONAL
Enrollment
252
Medical University of Innsbruck
Innsbruck, Tyrol, Austria
Association of MACE rates with peripheral atherosclerotic volume
Time frame: 5 years
Association of morbidity with peripheral atherosclerotic volume
Morbidity will be evaluated with quality of life assessment ("EQ-5D-3L", "IPAQ"
Time frame: 5 years
Comparison of predictive value of peripheral atherosclerotic volume with established risk scores for cardiovascular operations and interventions
Risk scores include STS Score and Euro Score
Time frame: 1 year
Association of the duration of the operation with peripheral atherosclerotic volume
Time frame: 30 days
Association of flow profiles of internal mammary artery with LIMA/RIMA graft patency rates
Time frame: 5 years
Association of the aortic clamp time with peripheral atherosclerotic volume
Time frame: 30 days
Association of the ICU stay with peripheral atherosclerotic volume
Time frame: 30 days
Association of the hospitalization duration with peripheral atherosclerotic volume
Time frame: 30 days
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