24-hour Ambulatory Blood Pressure Monitoring in Patients With Blood Pressure Above Thresholds in General Practice

University of Burgundy1,067 enrolled

Overview

High blood pressure (HBP) is a major modifiable cardiovascular risk factor which prevalence is gradually increasing. Reducing blood pressure (BP) significantly decreases cardiovascular morbi-mortality. Nevertheless, BP control remains insufficient: only 51% of French patients using antihypertensive drugs achieve the BP control targets. HBP is mostly diagnosed and managed in primary care. Nevertheless, office BP measurements are unreliable for BP control and poorer predict target organ damage. Ambulatory BP measurements are recommended for HBP diagnosis and follow-up. 24-hour ambulatory blood pressure monitoring (ABPM) is the most cost-effective strategy. Its superiority has been demonstrated for HBP diagnosis and cardiovascular prognosis. In France, ABPM is poorly available and little studied in primary care. Therefore, the investigators conducted a regional prospective study to analyze the feasibility and benefits of ABPM among primary care hypertensive patients in daily practice.

Study Type

OBSERVATIONAL

Enrollment

1,067

Conditions

Hypertension Blood Pressure Monitoring, Ambulatory Primary Health Care

Interventions

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion criteria: * patients aged over 18 years * with an office inclusion consultation systolic/diastolic BP≥ 140/90 mmHg * able to understand French language and to consent to participate in the study Exclusion criteria: * patients aged \< 18 years * with conditions preventing technically adequate ABPM (chronic atrial fibrillation) * with contraindications to ABPM (musculotendinous disease of the upper limb, past history of phlebitis of the upper limb or phlebitis in progress, past history of olecranon bursitis or bursitis in progress) * with previous ABPM in the 12 months prior to the inclusion consultation * pregnant or lactating women

Locations (7)

Groupements des Professionnels de Santé du Pays Beaunois

Beaune, France

SUSPENDED

Maison Universitaire de Santé et de Soins Primaires

Chenôve, France

RECRUITING

Cabinet de médecine générale

Garchizy, France

SUSPENDED

Maison de santé de Terre Pleine

Guillon, France

SUSPENDED

Maison de Santé Pluridisciplinaire

Montret, France

RECRUITING

Groupement des Professionnels de Santé de l'Auxois Sud

Pouilly-en-Auxois, France

RECRUITING

Maison de santé de l'Esplanade

Tournus, France

RECRUITING

Outcomes

Primary Outcomes

Prevalence of white-coat hypertension

Proportion of patients with normotension in ABPM (daytime systolic/diastolic BP\< 135/85 mmHg AND/OR nighttime BP\< 120/70 mmHg AND/OR 24-hour BP\< 130/80 mmHg) among the patients with primary care office measured BP≥ 140/90 mmHg