Muscle and physical activity play an important role in in growth, development and bone health in healthy children, especially during puberty. Children with inflammatory bowel disease (IBD) have lower level and intensity of physical compared to a control group. Several studies have shown that children with IBD have a lower bone mineral density (BMD) than general population, due to risk factors such as corticosteroid use, disease intensity, inflammation, malnutrition and a vitamin D deficiency. This low BMD is associated with an increased risk of fracture. A recent observational study found a positive and significant correlation between BMD in IBD patients and time spent in moderate to vigorous physical activity for one week (unpublished data).The present study aims to show a benefit of an adapted physical activity program on BMD in children and adolescents with IBD.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
15
Patients included in the control group will not benefit from the intervention in adapted physical activity. However, this will not affect their support. Patients will be seen by their specialist doctor as part of the usual management of their IBD.
Patients in the experimental group will have, in addition to their usual follow-up with their specialist doctor, an intervention in adapted physical activity at home, at the rate of 3 sessions (of a duration of 10 to 20 minutes) per week during 9 consecutive months.
Chu Amiens Picardie
Amiens, France
Hop Jeanne de Flandre Chu Lille
Lille, France
Change in total (whole body) Bone Mineral Density
Time frame: At 9 months
Change in vertebral BMD
Time frame: At 9 months
Change in femoral body BMD
Time frame: At 9 months
Change in time spent (minutes / day) in moderate to vigorous physical activity measured by accelerometry for 7 days
Time frame: At 9 months
Change in in fat mass measured by two-photon absorptiometry (%)
Time frame: At 9 months
Change in lean mass measured by two-photon absorptiometry (kg)
Time frame: At 9 months
Change IMPACT score III
related quality of life instrument in children with inflammatory bowel disease.
Time frame: At 9 months
Change in pediatrics crohn's disease activity index or pediatric ulcerative colitis activity index
Time frame: At 9 months
Change in biologic inflammatory parameters by decrease or increase C-reactive protein
Time frame: At 9 months
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