This study will compare two commonly used soft tissue grafting techniques (connective tissue graft, CTG vs Acellular Dermal Matrix, ADM) to augment the soft tissue at the time of lateral ridge augmentation procedure. Following ridge augmentation procedure, most of the times there is a need for soft tissue augmentation to change the quality of the tissue around future implant's site. To our knowledge, the influence of soft tissue augmentation at the time of ridge augmentation procedure has not been tested defects.
Research data and daily clinical observations reveal that implants with lack of surrounding keratinized mucosa KM (gingiva-like tissue that normally surrounds natural teeth) are more prone to persistent gingival inflammation, faster disease progression and compromised plaque control. Ridge augmentation procedure can alter the quality of tissue in the sites where it will receive dental implants. Soft tissue grating aims at changing the nature of peri-implant soft tissue by creating or increasing the zone of keratinized mucosa (KM) surrounding implants. CTG or ADM will be grafted at the same time of lateral ridge augmentation procedure. Specific aims for this project include the evaluation of: 1. To evaluate the quality of soft tissue regenerated with the use of the two available soft tissue grafts via histological analysis. 2. To evaluate whether CTG or ADM influences the outcomes of Guided Bone Regeneration (GBR) procedures. 3. To quantify the soft tissue augmentation achieved by the two available soft tissue grafts by direct clinical measurements after the healing
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
24
following the placement of the bone graft and the membrane, a CTG will be harvested and sutured to the membrane and then the flaps passively sutured on top on the bone and soft tissue graft
following the placement of the bone graft and the membrane, an ADM will be sutured to the membrane and then the flaps passively sutured on top on the bone and soft tissue graft
Following the placement of the bone graft and the membrane, the flaps passively sutured on top on the bone. No soft tissue graft will be added.
Unversity of Alabama at Birmingham, School of Dentistry
Birmingham, Alabama, United States
Measure Changes Clinically in Crestal Soft Tissue Thickness (in mm)
The changes in clinical vertical crestal soft tissue thickness by using an endodontic file and periodontal probe.
Time frame: From baseline to 6 months
Measure Changes Digitally in Crestal Soft Tissue Thickness (in mm)
The changes in soft tissue thickness digitally with superimposition of the intraoral scan and cone-bone computed tomography scan.
Time frame: From baseline to 6 months
Measure Changes Clinically in Soft Tissue Thickness at 4mm Apical From Gingival Margin
The changes in clinical soft tissue thickness at 4mm apical form the gingival margin by using an endodontic file and periodontal probe.
Time frame: From baseline to 6 months
Measure Changes Digitally in Soft Tissue Thickness at 4mm Apical Form Gingival Margin
The changes in soft tissue thickness digitally with superimposition of the intraoral scan and cone-bone computed tomography scan.
Time frame: From baseline to 6 months
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