The aim of this study is to evaluate the effectiveness of low dose scheme with dexmedetomidine as an adjuvant. Taking in consideration optimum intraoperative surgical conditions, best post-operative pain free experience, and more stable hemodynamic.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
40
10μg dexmedetomidine will be added to the injectate to be injected intrathecally
Menoufia University Hospitals
Shibīn al Kawm, Menoufia, Egypt
Density of motor and sensory blockade
Time frame: Intraoperative
Haemodynamic stability and total doses of IV fluids and vasopressors
Time frame: Intraoperative
Time to first postoperative rescue analgesic request
Time frame: 24 hour
The intraoperative patient and surgeon satisfaction (successful delivery)
Time frame: Intraoperative
The peak sensory level of block
Time frame: Intraoperative
Time from intrathecal injection to peak sensory block level
Time frame: Intraoperative
The time to two sensory block segment regression
Time frame: Intraoperative and 24 hour
Degree and duration of motor block
Time frame: Intraoperative and 24 hour
Intraoperative analgesic supplementation during operation
Time frame: Intraoperative
Postoperative pain scores for 24 hours
Time frame: 24 hour
Frequency and total dose of postoperative analgesics
Time frame: 24 hour
Intraoperative and postoperative sedation scores
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Time frame: Intraoperative and 24 hour
Incidence of side effects: nausea, vomiting, shivering, pruritus, respiratory depression, and desaturation.
Time frame: Intraoperative and 24 hour
Hospital in stay
Time frame: 24 hour
Time to S1 level sensory regression
Time frame: Intraoperative and 24 hour