Can Very Low Dose Rivaroxaban in Addition to Dual Antiplatelet Therapy (DAPT) Improve Thrombotic Status in Acute Coronray Syndrome (ACS) ACS

Inclusion Criteria: 1. Male and female patients aged 18 years or over 2. Have a diagnosis of acute coronary syndrome requiring treatment with dual antiplatelet therapy 3. Be willing and able to understand the Participant Information Sheet and provide informed consent 4. Agree to comply with the drawing of blood samples for the assessments 5. Not meet any of the exclusion criteria below Exclusion Criteria: 1. Male and female participants aged \< 18 years of age. 2. Patient unwilling or unable to give informed consent 3. Patients who might be pregnant or are breast-feeding 4. Active clinically significant bleeding 5. Patient who, in the opinion of the investigator, has condition considered to be a significant risk for major bleeding (such as current or recent gastrointestinal ulceration, presence of malignant neoplasm at high risk of bleeding, recent brain or spinal injury, recent brain, spinal or ophthalmic surgery, recent intracranial haemorrhage, known or suspected oesophageal varices, arteriovenous malformations, vascular aneurysms or major intraspinal or intracerebral vascular abnormalities) 6. Hepatic disease associated with coagulopathy and clinically relevant bleeding risk including cirrhotic patients with Child Pugh B and C 7. Patient with any contraindications to use of antiplatelet agents or anticoagulants 8. Hypersensitivity to the active substance or to any of the excipients listed in section 6.1 of Summary of Product Characteristics (SmPC) of Rivaroxaban 9. Concomitant treatment with any other anticoagulants e.g. unfractionated heparin (UFH), low molecular weight heparins (enoxaparin, dalteparin, etc.), heparin derivatives (fondaparinux, etc.), oral anticoagulants (warfarin, dabigatran etexilate, apixaban etc.) except under specific circumstances of switching anticoagulant therapy or when UFH is given at doses necessary to maintain an open central venous or arterial catheter 10. Concomitant treatment of ACS with antiplatelet therapy in patients with a prior stroke or a transient ischaemic attack (TIA) 11. Patient with ongoing active alcohol or substance abuse or demonstrates signs or clinical features of active substance abuse. 12. Patient with any major bleeding diathesis or blood dyscrasia at baseline (platelets\<70 x 109/l, Hb\<80 g/l, INR\>1.4, APTT\> x 2UNL, leucocyte count\< 3.5x 109/l, neutrophil count\<1x 109/l) 13. Patient currently enrolled in an investigational drug trial