A nationwide retrospective cohort study. To investigate the long-term patterns of transfusion and clinical outcomes of patients undergoing PCI.
A nationwide retrospective cohort study. Transfusion after PCI may increase a risk, but the long term effects after red blood cell transfusion is known. Longitudinal data is collected from administrative claims in the National Healthcare Insurance Service of Korea. All Korean patient date undergoing PCI inserting stent from January 1, 2011 to December 31, 2011 is extracted. Clinical outcomes until December 31, 2016 is investigated. Primary outcome is the incidence density of red blood cell transfusion. Secondary outcomes are the association of transfusion with major adverse clinical event (MACE) consisting all-cause death, revascularization, critically ill cardiovascular status, or stroke. Incidence density and time-dependent Cox proportional hazard regression is statistically analyzed.
Study Type
OBSERVATIONAL
Enrollment
48,786
Red blood cell transfusion on or after percutaneous coronary intervention
Samsung Medical Center
Seoul, Gang nam-Gu, Ilwon-Dong, South Korea
Incidence density of transfusion
5-year incidence density of red blood cell transfusion
Time frame: 5 years
Incidence density of MACE
5-year incidence densities of a major adverse clinical event (MACE) consisting of all-cause death, revascularization, critically ill cardiovascular status, and stroke
Time frame: 5 years
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