Preserving Left Colonic Artery During Radical Resection of Rectal Cancer

Third Military Medical University200 enrolled

Overview

To evaluate the feasibility and clinical significance of preserving left colonic artery in rectal cancer surgery.The investigators will focus on the effect of preserving left colonic artery during radical resection of rectal cancer on anastomotic leakage and oncology efficacy.

The investigators performed three-dimensional (3D) reconstruction to investigate the vascular anatomy, including the inferior mesenteric artery (IMA) and left colic artery (LCA),to help make pre-operative strategies of rectal cancer surgery.The investigators will preserving the left colonic artery during rectal cancer surgery and evaluate its feasibility and clinical significance.The investigators will focus on the effect of preserving left colonic artery during radical resection of rectal cancer on anastomotic leakage and oncology efficacy.

Study Type

OBSERVATIONAL

Enrollment

200

Conditions

Postoperative Complications Proteinosis

Interventions

Preserve the left colonic arteryPROCEDURE

Preservation of left colonic artery in rectal cancer surgery.

The left colonic artery is not preservedPROCEDURE

The left colonic artery was dissected in rectal cancer surgery.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Pathological biopsy confirmed adenocarcinoma of the rectum； 2. Preoperative assessment of tolerance to surgery without major organ dysfunction； 3. Patients must be able to understand and voluntarily sign written informed consent； 4. The surgical method is laparoscopic or robotic anterior rectal cancer resection. Exclusion Criteria: 1. The patient cannot tolerate the operation； 2. Refusal to sign informed consent； 3. Patients with distant metastasis of rectal cancer； 4. The surgical method was changed to miles or Hartman; 5. Unable to complete the follow - up

Locations (2)

zongming,Kang

Chongqing, Chongqing Municipality, China

zongming,Kang

Yuzhong, Chongqing Municipality, China

Outcomes

Primary Outcomes

The incidence of postoperative anastomotic leakage was compared between the two groups.

The incidence of anastomotic leakage within 30 days after surgery was compared between the intervention group and the control group.

Time frame: Within 30 days after surgery

The distant metastasis rates of rectal cancer between the two groups were compared.

The incidence of distant metastasis rectal cancer within two years after surgery was compared between the intervention group and the control group.

Time frame: Two years after surgery

The local recurrence rates of rectal cancer between the two groups were compared.

The incidence of local recurrence rectal cancer within two years after surgery was compared between the intervention group and the control group.

Time frame: Two years after surgery

The five-year survival rates of rectal cancer between the two groups were compared.

The 5-year survival rates of rectal cancer in the intervention group and the control group were compared.

Time frame: Five years after surgery

Data from ClinicalTrials.gov

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