The study was based on the clinical trial BCA-01 (NCT01368640) "Generation of prediction equations to analyze body composition of adults based on Bioelectrical Impedance Analysis (BIA)" and implicates an extension of the study collective. Aim of the study is to develop prediction equations for calculating FFM, TBW, ECW and SMM based on the gold standard reference methods ADP, DXA, MRI, D2O and NaBr on the one hand and measurement data of the BIA devices on the other hand.
Study Type
OBSERVATIONAL
Enrollment
38
Institute of Human Nutrition and Food Science
Kiel, Germany
BIA 5 and 50 kHz
Bioelectrical Impedance of 5 and 50 kHz for one body side
Time frame: 15 minutes
BIA 50 kHz
Bioelectrical Impedance of 50 kHz for all 4 extremities
Time frame: 15 minutes
Total body water
Total body water (TBW) by deuterium (D2O) dilution
Time frame: 15 minutes
Extracellular water
Extracellular water (ECW) by NaBr dilution
Time frame: 15 minutes
Fat-free mass
Fat-free mass by a 4-compartment model based on dual energy x-ray absorption (DXA), air displacement plethysmography (ADP), D2O dilution and weight
Time frame: 1 hour
Skeletal muscle mass
Skeletal muscle mass (SMM) by magnetic resonance imaging (MRI)
Time frame: 1 hour
Visceral adipose tissue
Visceral adipose tissue VAT by magnetic resonance imaging (MRI)
Time frame: 1 hour
Complete BIA
Bioelectrical Impedance of 1, 1.5, 2, 3, 7.5, 10, 15, 20, 30, 75, 100, 150, 200, 300, 500, 750 and 1,000 kHz for all body segments: right arm, left arm, right leg, left leg, trunk, right body side and left body side.
Time frame: 15 minutes
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