The Effects of Periodontal Therapy on Glycemic Control in Diabetic Patients

Taibah University44 enrolled

Overview

Is the non-surgical periodontal therapy can improve glycemic control in type 2 diabetic patients with chronic periodontitis?

The aim of the present study was to monitor the clinical outcomes and the metabolic response of non-surgical periodontal therapy in patients with chronic periodontitis and uncontrolled type 2 diabetes. Regarding clinical and metabolic parameters at baseline, no differences were displayed between two groups. However, at 3-months follow-up period the patients within a test group were demonstrated better clinical outcomes than patients in a control group

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Chronic Periodontitis, Generalized

Interventions

amoxicillin 500mg and metronidazole 400mgCOMBINATION_PRODUCT

metronidazole 400mg and amoxicillin 500mg three times daily for two weeks

Eligibility

Sex: ALLMin age: 40 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: Diagnosis of diabetes type 2 for more than five years Type 2 diabetes with HbA1c level from 7% to 9% at the last medical evaluation Diagnosis with chronic periodontitis Exclusion Criteria: Pregnancy * Alcoholism and smoking * Presence of any systemic disorders other than hypertension and diabetes * Diabetic major complications

Outcomes

Primary Outcomes

glycosylated haemoglobin (HbA1c)

Blood was taken from a peripheral vein to monitor HbA1c using high-performance liquid chromatography

Time frame: 3 months

Data from ClinicalTrials.gov

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