The fatty acid composition in blood and subcutaneous adipose tissue of infants that have an clinical indicated operation is studied.
Collection of: * subcutaneous adipose tissue of term infants and preterms after birth and at term during a clinically indicated operation. * blood before the operation. Measurement of the fatty acid composition (especially arachidonic acid and docosahexaenoic acid) in subcutaneous adipose tissue and blood. Aim is to compare the composition of the fatty acids in blood and adipose tissue of preterms at term and term infants. To calculate the fatty acid value in each infant the proportion of adipose tissue is determined with PEAPOD before discharge from hospital.
Study Type
OBSERVATIONAL
Enrollment
21
taking a sample of the adipose tissue during operation
taking a blood sample when a peripheral venous catheter is inserted before operation
Measurement of the total adipose tissue of the infant with PEAPOD (Air Displacement-Plethysmography, Infant Body Composition System, Cosmed, Rome, Italy)
University Hospital of Tuebingen
Tübingen, Germany
RECRUITINGFatty acid composition of the subcutaneous adipose tissue and plasma
Fatty acid composition of the subcutaneous adipose tissue and plasma of preterms at term compared to the composition of infants after birth (within 14 days).
Time frame: at the time of the operation
Fatty acid composition of the subcutaneous adipose tissue and plasma of preterms with abdominal problems
Change of fatty acid composition of the subcutaneous tissue and plasma from first to second operation in preterms with abdominal operations, enterostomy
Time frame: time of the first operation until discharge home (at a postnatal age of up to 4-5 months at the most in very preterm infants)
Fatty acid composition of the subcutaneous adipose tissue and plasma of preterms with abdominal problems and preterms without abdominal problems at term
Fatty acid composition of the subcutaneous adipose tissue and plasma of preterms at term compared to the composition of preterms at term with enterostomy.
Time frame: time of the first operation until discharge home (at a postnatal age of up to 4-5 months at the most in very preterm infants)
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