The main objection is to investigate molecular biology of myocardial damage during cardiac surgery procedures.
To assess outcomes after cardiac surgery procedures. To investigate serum level of myeloperoxidase, morphology of left atrium appendage, to perform genetic analysis and cell biology.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
2,000
On-pump CABG
Off-pump CABG
Pump-assisted CABG
Nikolai Bunenkov
Saint Petersburg, Non-US/Non-Canadian, Russia
RECRUITINGDeath within 30 days after procedure.
Death within 30 days after surgical procedure.
Time frame: within 30 days after procedure.
Acute myocardial infarction.
Acute myocardial infarction (ST-changes with troponin I \> 10 ng/ml).
Time frame: within 30 days after procedure.
Stroke.
Stroke (MRI changes or corresponding neurologist record).
Time frame: within 30 days after procedure.
Arrhythmia
Any type of arrhythmia including AV-block.
Time frame: within 30 days after procedure.
Renal dysfunction.
Renal dysfunction if serum creatinine greater than 25% of upper reference range.
Time frame: within 30 days after procedure.
Infection or febrile.
Infection or febrile (t\> 37 or CRP elevation or long regeneration of surgical wound).
Time frame: within 30 days after procedure.
Respiratory dysfunction.
Respiratory dysfunction (pulmonary ventilation longer than 2 days).
Time frame: within 30 days after procedure.
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Valve Repair Procedure without CABG (open heart procedure).
Valve Repair Procedure with CABG (open heart procedure).