Effect of Pneumoperitoneum on Remifentanil Requirements in the Surgical Pleth Index-guided Analgesia

Ajou University School of Medicine74 enrolled

Overview

The primary purpose of this study is to investigate the effect of pneumoperitoneum on remifentanil requirements in the surgical pleth index-guided analgesia for laparoscopic gastrectomy.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Enrollment

Conditions

Gastric Cancer

Interventions

High end-tidal CO2OTHER

maintaining of end-tidal CO2 with the range of 40-45 mmHg

Low CO2 groupOTHER

maintaining of end-tidal CO2 with the range of 30-35 mmHg

Eligibility

Sex: ALLMin age: 19 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * laparoscopic gastrectomy under general anesthesia Exclusion Criteria: * atypical hemoglobin disease, infective state, cardiovascular disease, peripheral vascular disease

Locations (1)

Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine

Suwon, Seoul, South Korea

Outcomes

Primary Outcomes

total dose of remifentanil

total dose of remifentanil to maintain for surgical pleth index \< 50

Time frame: through study completion, an average of 2 hours

Data from ClinicalTrials.gov

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