Risk Factors and Outcome of Biliary Complications Following Adult Living Donor Liver Transplantation

Assiut University50 enrolled

Overview

Liver transplantation (LT) is a live-saving therapy for patients with complicated chronic liver diseases and acute liver failure .Even though many complications can occur after LT, biliary complications (BC) are both common and potentially severe . a prospective study and retrospective part from hospital records. Aim of the study: 1. Detect frequency, risk factors for development of biliary complications post living donor liver transplantation, types (stricture anastomotic or not, leak, biloma, stone, cholangitis etc.…). 2. Evaluate outcomes of different biliary complications

Study Type

OBSERVATIONAL

Enrollment

Conditions

Liver Transplant; Complications

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adults more than 18 y with living donor liver transplantation in Al-Rajhy liver hospital , Assiut university,Egypt Exclusion Criteria: * pediatric liver transplantation * cadaveric liver transplantation

Locations (2)

Alrajhy center for hepatobiliary disorders

Asyut, Egypt

Outcomes

Primary Outcomes

Incidence of biliary complications

Biliary complications include biliary leak or stricture (anastomotic or non anastomotic), the investigator will record nature of complication , its time of presentation and number of hospital re-admissions due to biliary complications.

Time frame: 1 year after liver transplantation

Type of intervention done to each complication

Intervention is either non surgical (ERCP or PTD) or surgical revision with detailed description of each intervention and if the intervention is successful or not (biliary stricture resolved by MRCP, improvement of liver functions and symptoms)