Gum Arabic is a naturally produced gummy exudate from Acacia Senegal tree. It's a complex polysaccharide with proven prebiotic properties. Through its effect on intestinal bacteria, it's expected to reduce systemic levels of toxic bacterial metabolites and reduce inflammatory markers.By increasing fecal bacteria mass it's also expected to reduce blood urea level. These changes are potentially beneficial to hemodialysis patients who suffer from disturbed intestinal flora and a chronic inflammatory status. The investigators hypothesize that supplementing the diet of hemodialysis patients with Gum Arabic for four weeks would reduce inflammatory markers, increase total anti-oxidant capacity and reduce blood urea concentration.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
80
Instantly soluble granules of Gum Arabic; 100% Acacia Senegal
Maltodextrin powder, easily soluble
Doctor Salma Center for Kidney Diseases
Khartoum, Sudan
Highly sensitive C-reactive protein (hs CRP) level
Change in serum level of highly sensitive C-reactive protein.
Time frame: 4 weeks
Total anti-oxidant capacity
Change in serum total anti-oxidant capacity
Time frame: 4 weeks
Blood urea level
Change in urea blood level
Time frame: 4 weeks
Serum calcium
Change in serum calcium level
Time frame: 4 weeks
Serum phosphorus
Change in serum phosphorus level
Time frame: 4 weeks
Serum uric acid
Change in serum uric acid level
Time frame: 4 weeks
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