The aim of this review is to address clinical reliability, efficacy and safety of long-term treatment with oral D Mannose for the prevention of recurrent urinary tract infections (RUTIs) in females.
A comprehensive systematic MEDLINE, Embase, Cochrane search was performed for English language reports published before December 2018 using the term "recurrent urinary tract infections and d mannose." We searched Medline, Embase, and the Cochrane Register of Controlled Trials since January 2010 to December 2018. Eligible studies did not include non-oral therapy, local (vaginal) treatment in women with RUTIs. Study eligibility criteria- We identified eligible original articles. The heterogeneity of the available studies, their different rationale and aim, the assumption of d mannose for prophylaxis or treatment of recurrent UTIs need to be taken into account.
Study Type
OBSERVATIONAL
Enrollment
500
Urology Department Fondazione IRCCS Policlinico San Matteo
Pavia, Italy
research literature data on d mannose for prevention and treatment of recurrent urinary tract infections.
literature search of the Medline, Embase, and Cochrane Library databases
Time frame: January 2010-December 2018
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