Regional Blocks of Gynecological Surgeries

Cairo University273 enrolled

Overview

This study will be conducted on 273 patients of ASA grade I and II aged from 25 to 55 years and presented for elective vaginal surgeries such as vaginal hysterectomy, repair of prolapse Patients will be divided into three equal groups; group A control group for conventional epidural technique(n=91), group B for dural puncture epidural with 27G pencil point Whitacre spinal needle (n=91) and group C for dural puncture epidural with 25G pencil point Whitacre spinal needle(n=91). Randomization will be done using computer generated number and concealed using sequentially numbered sealed opaque envelope.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

TRIPLE

Enrollment

273

Conditions

Gynecologic Disease Requiring Vaginal Operation Under Neuraxial Anesthesia

Interventions

Standard Lumbar Epidural TechniquePROCEDURE

Standard Lumbar Epidural Technique at L4-5 inter-space using 0.5%Bupivacaine and Fentanyl.

25G Dural Puncture Epidural TechniquePROCEDURE

25G Dural Puncture Epidural Technique at L4-5 inter-space using 0.5%Bupivacaine and Fentanyl.

27G Dural Puncture Epidural TechniquePROCEDURE

27G Dural Puncture Epidural Technique at L4-5 inter-space using 0.5%Bupivacaine and Fentanyl.

Eligibility

Sex: FEMALEMin age: 25 YearsMax age: 55 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * ASA I and II * Height(150-170 cm) Exclusion Criteria: * patient refusal * hypersensitivity to local anesthetic drugs * bleeding disorders and coagulopathy(platelets count less than 80000,INR less than 1.5 or therapeutic dose of anticoagulant).

Locations (2)

Department of Anesthesia, Surgical ICU, and Pain Management

Cairo, Egypt

Reham Ali Abdelrahman

Cairo, Egypt

Outcomes

Primary Outcomes

incidence of bilateral sacral blockade

Sensory blockade was evaluated using a non-traumatic pinprick stimulus starting at the S2 dermatome and moving in a caudad direction (measured every 2 minutes)