This study is designed as a prospective, observational, multi-centre study to evaluate the efficacy and safety of Teneligliptin when switched from other DPP-4 inhibitors in type 2 DM with inadequate glycemic control
Study Type
OBSERVATIONAL
Enrollment
2,983
Ajou University Hospital
Suwon, Gyeonggi-do, South Korea
Change in HbA1c
To assess change from baseline in glycated hemoglobin (HbA1c)
Time frame: at 12 weeks after switching to Teneligliptin
Change in HbA1c
To assess change from baseline in HbA1c
Time frame: at 24, 52 weeks after switching to Teneligliptin
Change in FBG
To assess change from baseline in fasting blood glucose (FBG)
Time frame: at 12, 24, 52 weeks after switching to Teneligliptin
Change in body weight, BMI
To assess change from baseline in body weight and body mass index (BMI)
Time frame: at 12, 24, 52 weeks after switching to Teneligliptin
Change in lipid profile(Total cholesterol, LDL cholesterol, HDL cholesterol)
To assess change from baseline in serum lipid profile (total cholesterol, LDL and HDL cholesterol, triglyceride)
Time frame: at 12, 24, 52 weeks after switching to Teneligliptin
The percentage of patients with HbA1c <7.0% and <6.5%
To assess the percentage of patients with HbA1c \<7.0% and \<6.5%
Time frame: at Weeks 12, 24, and 52 of teneligliptin treatment
The percentage of patients with a decrease from baseline in HbA1c
To assess the percentage of patients with a decrease from baseline in HbA1c by ≥0.3% and ≥ 0.5%
Time frame: at Weeks 12, 24, and 52 of teneligliptin treatment
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Safety Outcome
To assess the safety of teneligliptin treatment(AE, ADR, SAE etc.)
Time frame: at Weeks 12, 24, and 52 of teneligliptin treatment