Comparing pre-operative transbronchial localization under augmented fluoroscopy and intra-operative transbronchial localization using electromagnetic navigation bronchoscopy system for small lung nodules.
Using electromagnetic navigation bronchoscopy (ENB), transbronchial localization can be performed in the operating room (OR) under general anesthesia without extra radiation exposure, which is expected to reduce the discomfort for the patient during localization. This study will be carried out at the Hsinchu Branch of National Taiwan University Hospital. It is expected that 40 patients with pulmonary nodules will be randomly assigned into two groups. One group will receive bronchoscopic dye localization in the hybrid examination room equipped with cone-beam computed tomography, and the other group will receive ENB-guided dye localization in OR. The primary goal of the study was to compare the localization duration of the two groups of patients, the total dose of radiation exposure during localization and the incidence of location-related complications, and the secondary goals were the results of the surgical procedure, including the surgical duration.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
40
Bronchoscopic dye marking under CBCT-augmented fluoroscopic guidance
Bronchoscopic dye marking with ENB system
National Taiwan University Hospital, Hsin-Chu Branch
Taipei, Hsin-Chu County, Taiwan
RECRUITINGSuccessful localization
Discrepancy from lesion to marking: less than 1 cm
Time frame: 2 days
Successful resection
Lesion contained in first resected specimen
Time frame: 2 days
Localization duration
Total time span of localization procedure
Time frame: 1 day
Total radiation exposure
Radiation during entire localization procedure
Time frame: 2 days
Complication
Procedure related complication
Time frame: 14 days
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.