Analysis of Non-Invasively Collected Microneedle Device Samples From Mild Plaque Psoriasis for Use in Transcriptomics Profiling

Inclusion Criteria: * Participant has a history of chronic plaque psoriasis vulgaris for at least 6 months prior to the screening visit * Participant has had stable psoriasis conditions for at least 3 months before screening (information obtained from medical chart or participant's physician, or directly from the participant) * Participant has plaque psoriasis covering \>= 1% but \< 10% of his total BSA on Day 1 * For Group A: Participant has one psoriasis target lesion or individual lesions within the same anatomical region (excluding palms, soles, face, scalp, and genitals), with a target lesion severity score (TLSS) score of \>= 6 on Day 1 allowing the collection of three microneedle device samples and one biopsy sample * For Group B: Participant has one psoriasis target lesion or individual lesions within the same anatomical region (excluding palms, soles, face, scalp, and genitals), with a TLSS score of \>= 6 on Day 1 allowing the collection of one microneedle device sample per visit (replicating the extraction on the same area at each visit) and one biopsy sample Exclusion Criteria: * Participant is a female who is breastfeeding, pregnant, or who is planning to become pregnant during the study * Participant has evidence of erythrodermic, pustular, predominantly guttate psoriasis, or drug-induced psoriasis * Participant has a history of skin disease or presence of skin condition that, in the opinion of the investigator, would interfere with the sample collection or interpretation * Participant is known to have immune deficiency or is immunocompromised * Participant has a history of cancer or lymphoproliferative disease within 5 years prior to Day 1. Participants with successfully treated nonmetastatic cutaneous squamous cell or basal cell carcinoma and/or localized carcinoma in situ of the cervix are not to be excluded