Presepsin (soluble CD14 subtype) is a novel marker with growing body of evidence supporting its accuracy and value for the diagnosis of sepsis. Patients with sepsis showed higher Prsepsin levels compared to those with SIRS. In addition the increase in Prsepsin levels correlates well with sepsis severity. Red cell distribution width variations are increased in a variety of medical conditions such as congestive heart failure, acute myocardial infarction, pulmonary embolism, pneumonia, critical illness, and cardiac arrest , and is a predictor of mortality in the general population. we aim to compare between Presepsin (soluble CD14) and RDW as prognostic markers in critically-ill patients with sepsis.
Study Type
OBSERVATIONAL
Enrollment
200
A total of 100 sepsis patients, Red Cell Distribution Width (RDW) was used as prognostic marker.
: A total of 100 sepsis patients, Presepsin (sCD14-ST) was used as prognostic marker.
Ain Shams University Hospitals
Cairo, Egypt
Mortality during intensive care unit stay
Time frame: 28 days
Length of ICU stay
Time frame: assessed up to 3 months
Need for readmission to ICU
Time frame: assessed up to 3 months
Ventilatory support duration
Time frame: assessed up to 3 months
Number of participants who need renal replacement therapy
Time frame: assessed up to 3 months
Number of participants who need inotropic or vasopressor support
Time frame: assessed up to 3 months
Transfusion requirements (blood and blood products)
Time frame: assessed up to 3 months
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