This 2-year trial is intended to be used to study breast cancer patients through forward-looking generation design through collaboration between Chinese and Western medical teams. The whole study consists of 2 stages, stage I comprises a cross-sectional study-baseline and stage II is a cohort for outcome evaluation and follow-up study across a 3-year period. To provide an empirical basis for combined TCM treatment in the Breast Cancer Research Team and to publish that as a reference for future TCM and Western medicine in integrative cancer treatment.
Breast cancer is a major health issue for women worldwide and has increased exponentially in the last decades. Improved earlier detection combined with adjuvant systemic therapy is responsible for much of the reduction in cause-specific mortality from breast cancer. Chemotherapy after surgery can decrease the risk of recurrence and is often used as routine treatment in clinic. Because of the fact that a considerable number of patients seek for traditional Chinese medicine (TCM) during adjuvant chemotherapy, it is thus need to evaluate the correlation between TCM treatment and prognosis. The investigators design a single center, prospective cohort study began in November 2018 in Kaohsiung, Taiwan. A sample of 104 participants diagnosed with early breast cancer was recruited from Breast Cancer Research Team and are followed up every 3 to 6 months till October 2023. Detailed information of participants includes general information, history of cancer, quality of life, side effects of chemotherapy and safety of treatment, body constitution of TCM and meridian energy analysis is taken face-to-face at baseline.
Study Type
OBSERVATIONAL
Enrollment
310
All Chinese herbal products prescribed from TCM physicians in our hospital during patients receiving adjuvant chemotherapy
Kaohsiung Chang Gung Memorial Hospital
Kaohsiung City, Taiwan
RECRUITINGdisease-free survival
3-year disease-free survival
Time frame: 3 years
QOLs measurement-1
Functional Assessment of Cancer Therapy - Breast Cancer(FACT-B)
Time frame: 6 months
QOLs measurement-2
Eastern Cooperative Oncology Group (ECOG)
Time frame: 6 months
TCM pattern
Body Constitution Questionnaire (BCQ)
Time frame: 6 months
meridian energy
Meridian Energy Analysis Device (MEAD)
Time frame: 6 months
Side effects of adjuvant chemotherapy
Common Terminology Criteria for Adverse Events (CTCAE)
Time frame: 6 months
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