Protein Ingestion and Skeletal Muscle Atrophy

N/ACompletedNCT03797781

University of Exeter33 enrolled

Overview

The effect of different protein intakes on skeletal muscle atrophy during short term unilateral leg immobilisation.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

SINGLE

Enrollment

Conditions

Muscle Atrophy

Interventions

Lower limb immobilisation (leg brace) with varying levels of protein intakeOTHER

Single leg immobilisation via leg brace and crutches, the groups have different amounts of protein intake

Eligibility

Sex: MALEMin age: 18 YearsMax age: 35 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * BMI \>18 and \<28 no prescription medications or current illness. Exclusion Criteria: * BMI \<18 and \>28 current prescription medication no history of leg injury. * Smoker * Medical conditions including (cardiovascular disease ((e.g. hypertension)), metabolic disease ((e.g. type 2 diabetes)), any personal or family history of deep vein thrombosis.

Locations (1)

Sport and Health Science

Exeter, Devon, United Kingdom

Outcomes

Primary Outcomes

Muscle size

Time frame: 3 days

Secondary Outcomes

Muscle strength

Time frame: 3 days

Data from ClinicalTrials.gov

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