The Effects Of DBS Of Subthalamıc Nucleus On Functionality In Patıents With Parkinson's Disease: Short-Term Results

Mustafa Kemal University10 enrolled

Overview

Parkinson's disease is a progressive chronic neurodegenerative disease. In cases where drug treatment is insufficient and drug use is not possible due to drug side effects, highly effective and low-risk surgical treatment options could be used. In Parkinson's Disease; findings such as chest wall rigidity and weakness of the respiratory muscle strength occur. The aim of this study was to determine the effect of preop and postop DBS surgery on respiratory muscle strength, respiratory function and physical performance in patients with Parkinson's disease.

In the study, at least 10 patients with Parkinson's disease who had DBS surgery in Mustafa Kemal University Research and Practice Hospital, Department of Brain and Nerve Surgery will be evaluated. Demographic-physical features, pulmonary functions, respiratory muscle strength, exercise capacity, functionality, and muscle strength will be evaluated

Study Type

INTERVENTIONAL

Allocation

Purpose

SUPPORTIVE_CARE

Masking

NONE

Enrollment

Conditions

Parkinson Disease Surgery Respiration; Decreased

Eligibility

Sex: ALLMin age: 40 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Lack of any neurological disease other than Parkinson's * DBS surgery to be performed in the STN region Exclusion Criteria: * Patients with advanced cognitive impairment * Patients with pulmonary, neurological and orthopedic diseases affecting functionalities * Pregnancy * Patients in whom the stimulation was canceled due to infection after surgery.

Outcomes

Primary Outcomes

Functional exercise capacity

6 minute walking test

Time frame: Change from Baseline Functional exercise capacity at 3 months(Pre-op,Post-op Off, Post-op 1. month, Post-op 3. Month), an average of 3 months

Secondary Outcomes

Pulmonary functions

Spirometry

Time frame: Change from Pulmonary functions at 3 months(Pre-op,Post-op Off, Post-op 1. month, Post-op 3. Month), an average of 3 months

Inspiratory and expiratory muscle strength (MIP, MEP)

Mouth pressure device

Time frame: Change from Inspiratory and expiratory muscle strength (MIP, MEP) at 3 months(Pre-op,Post-op Off, Post-op 1. month, Post-op 3. Month), an average of 3 months

Muscle strength

Muscle Testing Device (N)

Time frame: Change from Peripheral muscle strength at 3 months(Pre-op,Post-op Off, Post-op 1. month, Post-op 3. Month), an average of 3 months

Grip Test (Peripheral muscle strength)

Hand Held Dynamometer (kgf)