Early Debridement Within 24 Hours After Surgery for Wound Healing of Abdominal Incision

First Affiliated Hospital Xi'an Jiaotong University480 enrolled

Overview

Wound healing after surgery is a complex procedure. Liquefaction of the fat and necrosis of inactivated tissue, as well as blood clots are always accumulated mostly within 24 hours after surgery. As such, early debridement within 24 hours after surgery might improve the healing of the wounds. This study is designed to compare the impact of early debridement of the wound versus regular dressing (24 hours later) on the wound healing. 100 patients will be included in this study, and divided into 2 groups randomly. Then, the healing of the wound, stitch removal time, incidence of incision complications will be compared between the two groups.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

480

Conditions

Surgical Wound

Interventions

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * the patient with major abdominal incision. Exclusion Criteria: * Pregnant woman * Patient with diabetes * Patient with a history of cardiovascular disease, including coronary heart disease and stroke. * Severe lung diseases such as COPD and asthma * Patients undergoing emergent surgery or infectious surgery * Patients with surgical site infection or abdominal abscess * No autonomy, inability or unwillingness to participate in follow-up

Outcomes

Primary Outcomes

healing time, d (day)

since the ending of surgery to stitches off.

Time frame: From date of surgery to the date of stitches off (up to 1 month)

Secondary Outcomes

incidence of incision complications

The incision complications include infection, dehiscence, fat liquefaction, etc.

Time frame: From the date of surgery to stitches off (up to 1 month)