Metabolic surgery, as a recognition treatment option for patients with clinical morbid obesity, is gaining increasing appreciation. In addition to substantial weight loss, emerging studies have highlighted that metabolic surgery can substantially ameliorate obesity-related metabolic diseases, including but not limited to type 2 diabetes mellitus (T2DM), hypertension, dyslipidemia, obstructive sleep apnea-hypopnea syndrome (OSAHS) and polycystic ovary syndrome (PCOS)in severely obese patients. However, further investigations with larger sample size and longer observation time still needed to clarity the efficacy and safety of metabolic surgery in Chinese patients with obesity and encouraging future research in this field.
Study Type
OBSERVATIONAL
Enrollment
50,000
Beijing Friendship Hospital
Beijing, Beijing Municipality, China
the excess weight loss effect of different metabolic surgeries after 1year
Percent excess weight loss (%EWL), %EWL=\[(initial weight)-(post-op weight)\]/\[(initial weight)-(ideal weight)\] (in which "ideal weight" is defined by the weight corresponding to a BMI of 25 kg/m2)
Time frame: 1 year after surgery
the adverse events rate of different metabolic surgeries
show the surgical safety by 30 days follow-up according to guideline（such as: bleeding, leak, obstruction, re-operation for complication）
Time frame: 30 days after surgery
the excess weight loss effect of metabolic surgery with long-time follow-ups
Percent excess weight loss (%EWL), %EWL=\[(initial weight)-(post-op weight)\]/\[(initial weight)-(ideal weight)\] (in which "ideal weight" is defined by the weight corresponding to a BMI of 25 kg/m2)
Time frame: 3 years
the excess weight loss effect of metabolic surgery with long-time follow-ups
Percent excess weight loss (%EWL), %EWL=\[(initial weight)-(post-op weight)\]/\[(initial weight)-(ideal weight)\] (in which "ideal weight" is defined by the weight corresponding to a BMI of 25 kg/m2)
Time frame: 5 years
the excess weight loss effect of metabolic surgery with long-time follow-ups
Percent excess weight loss (%EWL), %EWL=\[(initial weight)-(post-op weight)\]/\[(initial weight)-(ideal weight)\] (in which "ideal weight" is defined by the weight corresponding to a BMI of 25 kg/m2)
Time frame: 10 years
the glycemic control level of metabolic surgery with long-time follow-ups
the change of HbA1c, glucose level, C-peptide and insulin levels
Time frame: 1 year after surgery
the glycemic control level of metabolic surgery with long-time follow-ups
the change of HbA1c, glucose level, C-peptide and insulin levels
Time frame: 3 year after surgery
the glycemic control level of metabolic surgery with long-time follow-ups
the change of HbA1c, glucose level, C-peptide and insulin levels
Time frame: 5 year after surgery
the glycemic control level of metabolic surgery with long-time follow-ups
the change of HbA1c, glucose level, C-peptide and insulin levels
Time frame: 10 year after surgery
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