A total of 240 consecutive SLE patients fulfilling the SLICC classification criteria was evaluated. Sixty two patients who met the inclusion criteria were randomly assigned to the exercise group (n=32) or the control group (n=30). Patients in the exercise group performed a program of strengthening, stretching and resistance upper limbs exercises, of 30 minutes duration daily, for 12 weeks. Performance of daily activities was evaluated with the DASH and HAQ questionnaires, grip and pinch strength with the Jamar dynamometer and pinch gauge tools respectively, dexterity with the Purdue pegboard test and the quality of life with the LUPUSQoL questionnaire at 0, 6, 12 (end of the exercise program) and 24 weeks for both groups. SLE activity and cumulative organ damage were evaluated with the SLE disease activity index 2000 (SLEDAI-2K) and SLICC/ACR-DI, respectively.
A total of 240 consecutive SLE patients fulfilling the SLICC classification criteria was evaluated. Sixty two patients who met the inclusion criteria \[age\>18, upper limb arthralgias, and DASH (Disabilities of the Arm, Shoulder, and Hand) questionnaire score\>10)\] were randomly assigned to the exercise group (n=32) or the control group (n=30). Patients in the exercise group performed a program of strengthening, stretching and resistance upper limbs exercises, of 30 minutes duration daily, for 12 weeks. Performance of daily activities was evaluated with the DASH and HAQ questionnaires, grip and pinch strength with the Jamar dynamometer and pinch gauge tools respectively, dexterity with the Purdue pegboard test and the quality of life with the LUPUSQoL questionnaire at 0, 6, 12 (end of the exercise program) and 24 weeks for both groups. SLE activity and cumulative organ damage were evaluated with the SLE disease activity index 2000 (SLEDAI-2K) and SLICC/ACR-DI, respectively.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
62
General Hospital of Athens 'Laiko'
Athens, Attica, Greece
General Hospital of Elefsina 'Thriasio'
Elefsina, Attica, Greece
change of DASH questionnaire
Hand function was measured with DASH Questionnaire
Time frame: Baseline, 6, 12, 24 weeks
change of HAQ questionnaire
Hand function was measured with HAQ Questionnaire
Time frame: Baseline, 6, 12, 24 weeks
change of Grip strength
Grip strength was measured with Jamar Dynamometer
Time frame: Baseline, 6, 12, 24 weeks
change of Pinch strength
Pinch strength was measured with Jamar pinch gauge
Time frame: Baseline, 6, 12, 24 weeks
change of Dexterity
Dexterity was measured with Purdue Pegboard test
Time frame: Baseline, 6, 12, 24 weeks
change of Quality of Life
Quality of Life was measured with LupusQoL Questionnaire
Time frame: Baseline, 6, 12, 24 weeks
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