This study investigates the utility of thin bronchoscope and virtual bronchoscopic navigation system (targeted bronchial washing) for detection of M. tuberculosis and resistant-conferring mutations in patients with pulmonary tuberculosis. Time to appropriate treatment and stain/culture conversion are also evaluated.
Comparisons of detection rate of M. tuberculosis and resistant-conferring mutations between patients who perform CT-guided conventional bronchoscope and patients who perform VBN-guided thin bronchoscope.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
88
targeted washing at more adjacent TB lesion using thin bronchoscope and virtual bronchoscopic navigation system
Pusan National University Hospital
Busan, South Korea
detection of M. tuberculosis and resistant-conferring mutations
evaulation by sensitivity, specificity, PPV and NPV
Time frame: 2months after procedure
time to appropriate treatment and stain/culture conversion
date of treatment initiation and stain/culture negative conversion
Time frame: 6months after procedure
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