The objective of this proposal is to develop and validate diagnostic and prognostic (including short-term and long-term prognoses) prediction models for patients with venous thromboembolism (VTE) in China.
Venous thromboembolism (VTE), which clinically manifests as deep vein thrombosis (DVT) and pulmonary embolism (PE), is one of the leading causes of mortality that need to be accurately diagnosed and effectively managed. Although a number of clinical decision rules in the domain of VTE have been presented in the literature, such as the well-known prediction models developed by Wells and colleagues, the prognostic models to assess VTE recurrence risk in patients who suffered from a VTE or the Pulmonary Embolism Severity Index (PESI) for short-term mortality risk in PE patients, and various other diagnostic models for both DVT and PE. They are few designed for Chinese patients. The primary objective of this proposal is to develop and validate diagnostic and prognostic (including short-term and long-term prognoses) prediction models for patients with VTE in China.
Study Type
OBSERVATIONAL
Enrollment
4,000
Shanghai Tenth People's Hospital, Tongji University
Shanghai, Shanghai Municipality, China
RECRUITINGDeath from all causes
Death from all causes during follow-up
Time frame: 5-year
Death from all causes
Death from all causes during hospitalization
Time frame: 30-day
Number of Participants with Recurrent VTE
Recurrent symptomatic DVT confirmed by venography or color duplex sonography or recurrent symptomatic pulmonary embolism confirmed by ventilation-perfusion scanning, CTPA, or pulmonary angiogram.
Time frame: 5-year
Number of Participants with Chronic Thromboembolic Pulmonary Hypertension(CTEPH)
CTEPH can be diagnosed by an echocardiogram or a CTPA.
Time frame: 5-year
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