Comparison of Measured Caloric Expenditure Versus Administered Calories in Neonates

Boston Children's Hospital

Overview

The investigators have created and validated a device that allows us to accurately measure how many calories a baby consumes every day. The purpose of this study is to compare how many calories a baby consumes with how many calories are provided in a population of newborn infants and children. This may help clinicians to better understand how to feed babies during times of critical illness.

Study Type

OBSERVATIONAL

Conditions

Calorie Overload Calorie Deficiency

Interventions

Monitoring of energy expenditureDEVICE

Continuous monitoring of energy expenditure.

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: 1. Mechanically ventilated neonates, infants and children, regardless of age, up to 10 kg 2. Inpatients in the cardiac (8S), medical-surgical (7S) or neonatal (7N) intensive care unit 3. Assent of patient's intensive care attending physician 4. Written parental informed consent. 5. Patient on conventional mechanical ventilation on a Servo I or Servo U ventilator with fraction of inspired oxygen \<80%. Exclusion Criteria: 1. Clinically significant tracheo-esophageal fistula 2. Measured ETT leak \>20% (i.e. difference between inspiratory and expiratory tidal volumes) 3. Patient on high frequency oscillatory ventilation or high frequency jet ventilation.

Outcomes

Primary Outcomes

Average caloric expenditure

Number of calories consumed

Time frame: through study completion, an average of 3 days

Data from ClinicalTrials.gov

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