The purpose of this study prospective observational study is to determine cognitive dysfunction incidence after thoracic surgery. We also evaluate evaluate the role of cerebral oxygen desaturations and hypertension as risk factors for post-operative cognitive dysfunction (POCD) in patients undergoing lung resection.
Study Type
OBSERVATIONAL
Enrollment
100
Before general anesthesia, continuous monitoring of cerebral oxygenation(rSO2) was started using an INVOS 5100 (Somaneic, Tro, MI) .Patient cognitive function was assessed using Mini-Mental State Examination (MMSE) on the day before surgery (baseline) and then after 1 day after surgery.
azienda ospedaliero universitaria Sant'Andrea
Roma, Italy
incidence of cognitive dysfunction after thoracic surgery
A decrease in Mini-Mental State Examination (MMSE) score \> 2 points from baseline was defined as Postoperative cognitive dysfunction (POCD)
Time frame: change of MMSE score from the day before surgery (baseline) at 1 day after surgery
role of cerebral oxygen desaturations as risk factors for POCD in patients undergoing lung resection.
monitoring values of cerebral saturation during intraoperative period:Cerebral desaturation was defined as a reduction of rSO2 during OLV of more than 20% from the baseline value
Time frame: change of cerebral saturation from baseline(before surgery) at intraoperative measure
role of hypertension as risk factors for POCD in patients undergoing lung resection.
monitoring values of blood pressure during intraoperative period
Time frame: change of blood pressure from baseline(before surgery) at intraoperative measure
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